Product Overview
Indotecan | T15578 | TargetMol Chemicals
CAS: 915303-09-2
Smiles: COc1cc2c3C(=O)c4cc5OCOc5cc4-c3n(CCCN3CCOCC3)c(=O)c2cc1OC
Formula: C26H26N2O7
Pathway: DNA Damage/DNA Repair
Target: Topoisomerase
Receptor: N/A
Bioactivity: Indotecan is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).
Molecular Weight: 478, 501