Product Overview
Irinotecan | T6228 | TargetMol Chemicals
CAS: 97682-44-5
Smiles: CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12
Formula: C33H38N4O6
Pathway: Autophagy|||DNA Damage/DNA Repair
Target: Topoisomerase|||Autophagy
Receptor: N/A
Bioactivity: Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death.
Molecular Weight: 586, 689
