Product Overview
Isodunnianol | TN4286 | TargetMol Chemicals
CAS: 139726-30-0
Smiles: Oc1ccc(CC=C)cc1-c1cc(CC=C)cc(Oc2ccc(CC=C)cc2)c1O
Formula: C27H26O3
Pathway: Immunology/Inflammation|||Neuroscience|||NF-Κb
Target: NOS|||NF-κB|||ROS|||AChR
Receptor: N/A
Bioactivity: Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. Isodunnianol, dunnianol, and Macranthol have anti-inflammatory activity, they can increase NAG-1(multiple targets related to inflammation) activity 1.5 -3.0 fold and decrease cellular oxidative stress by 40-65%, they show substantial activity against iNOS.
Molecular Weight: 398, 5