Product Overview
Isolicoflavonol | TN1783 | TargetMol Chemicals
CAS: 94805-83-1
Smiles: CC(C)=CCc1cc(ccc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O
Formula: C20H18O6
Pathway: Metabolism
Target: Lipid
Receptor: N/A
Bioactivity: Isolicoflavonol inhibits Human carboxylesterase 2 (hCES2A) which is a key target to ameliorate the intestinal toxicity triggered by irinotecan that causes severe diarrhea in 50%-80% of patients receiving this anticancer agent.
Molecular Weight: 354, 358