Product Overview
JAK/HDAC-IN-1 | T15605 | TargetMol Chemicals
CAS: 2284621-75-4
Smiles: ONC(=O)CCCCCn1cc(Nc2ncc(Cl)c(Nc3ccc(Cl)cc3)n2)cn1
Formula: C19H21Cl2N7O2
Pathway: Angiogenesis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Tyrosine Kinases|||JAK|||HDAC
Receptor: N/A
Bioactivity: JAK/HDAC-IN-1 is an effective JAK2/HDAC dual inhibitor (IC50s: 4 and 2 nM for JAK2 and HDAC). It also shows antiproliferative and proapoptotic activities in several hematological cell lines.
Molecular Weight: 450, 32
