Product Overview
JH-II-127 | T7155 | TargetMol Chemicals
CAS: 1700693-08-8
Smiles: CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12
Formula: C19H21ClN6O3
Pathway: Autophagy
Target: LRRK2
Receptor: N/A
Bioactivity: JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, G2019S LRRK2 and A2016T LRRK2 (IC50s = 6.6, 2.2, and 47.7 nM, respectively),
Molecular Weight: 416, 87
