K145 hydrochloride | TQ0138

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€207.00 - €1,806.00
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TMC-TQ0138
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Product Overview

K145 hydrochloride | TQ0138 | TargetMol Chemicals

CAS: 1449240-68-9

Smiles: Cl.CCCCOc1ccc(CC\C=C2/SC(=O)N(CCN)C2=O)cc1

Formula: C18H25ClN2O3S

Pathway: Apoptosis|||GPCR/G Protein

Target: Apoptosis|||S1P Receptor

Receptor: N/A

Bioactivity: K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity, with IC50 of 4.3 µM and Ki of 6.4 µM. K145 hydrochloride can induce apoptosis and has strong antitumor activity.

Molecular Weight: 384, 92

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