Product Overview
KPT9274 | T4354 | TargetMol Chemicals
CAS: 1643913-93-2
Smiles: Nc1ccc(\C=C\C(=O)NCc2cc3cc(cc(-c4ccc(F)cc4)c3o2)-c2ccc(cc2)C(=O)N2CCC(F)(F)CC2)cn1
Formula: C35H29F3N4O3
Pathway: Cytoskeletal Signaling|||Metabolism
Target: NAMPT|||PAK
Receptor: N/A
Bioactivity: KPT-9274 is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.
Molecular Weight: 610, 637