Product Overview
KU60019 | T2474 | TargetMol Chemicals
CAS: 925701-49-1
Smiles: C[C@H]1CN(CC(=O)Nc2ccc3Sc4c(Cc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)C[C@@H](C)O1
Formula: C30H33N3O5S
Pathway: DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: ATM/ATR
Receptor: N/A
Bioactivity: Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.
Molecular Weight: 547, 67