L-2-Hydroxyglutaric acid | T13749

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TMC-T13749
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Product Overview

L-2-Hydroxyglutaric acid | T13749 | TargetMol Chemicals

CAS: 13095-48-2

Smiles: O[C@@H](CCC(O)=O)C(O)=O

Formula: C5H8O5

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively. L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation.

Molecular Weight: 148, 114

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