Product Overview
Latifolin | TN4420 | TargetMol Chemicals
CAS: 10154-42-4
Smiles: COc1cc(OC)c(cc1O)[C@H](C=C)c1ccccc1O
Formula: C17H18O4
Pathway: Apoptosis|||Autophagy|||GPCR/G Protein|||Immunology/Inflammation|||Microbiology/Virology|||Neuroscience|||NF-Κb
Target: IL Receptor|||IκB/IKK|||TNF|||NOS|||NF-κB|||COX|||Nrf2|||Prostaglandin Receptor|||Antifection|||Autophagy
Receptor: N/A
Bioactivity: Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifolin displays potent anticarcinogenic phase II marker enzyme, quinone reductase (QR) inducing activity and high chemopreventive indices. Latifolin also shows antifungal activity against white- and brown-rot fungi.
Molecular Weight: 286, 32
