Product Overview
LC3-mHTT-IN-AN1 | T8081 | TargetMol Chemicals
CAS: 486443-73-6
Smiles: Oc1cc(\C=C2/C(=O)Nc3ccc(Br)cc23)cc(Br)c1O
Formula: C15H9Br2NO3
Pathway: Autophagy|||Others
Target: Others|||Autophagy
Receptor: N/A
Bioactivity: LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound that interacts with both mutant huntingtin protein (mHTT) and LC3B. LC3-mHTT-IN-AN1 targeted mHTT to autophagosomes reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Molecular Weight: 411, 049
