Product Overview
Liriodenine | TN1875 | TargetMol Chemicals
CAS: 475-75-2
Smiles: O=C1c2ccccc2-c2c3OCOc3cc3ccnc1c23
Formula: C17H9NO3
Pathway: Apoptosis|||Proteases/Proteasome
Target: BCL|||Caspase|||p53
Receptor: N/A
Bioactivity: Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial ischaemia reperfusion, through inhibition of Na+ and the Ito channel. Liriodenine also has antimuscarinic properties, the antimuscarinic characteristics are similar to those of 4-diphenylacetoxy-N-methylpiperidine (4-DAMP, smooth muscle selective M3 antagonist), it may act as a selective M3 receptor antagonist in canine tracheal smooth muscle.
Molecular Weight: 275, 263
