Product Overview
Lyn peptide inhibitor | TP2008 | TargetMol Chemicals
CAS: 222018-18-0
Smiles:
Formula: C115H184N30O24
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro. Inhibits airway eosinophilic inflammation in mouse model of asthma.
Molecular Weight: 2370, 91
