Product Overview
M2I-1 | T4647 | TargetMol Chemicals
CAS: 312271-03-7
Smiles: CC(C)CN(CC(C)C)c1ccc(C=C2C(=O)NC(=S)NC2=O)cc1[N+]([O-])=O
Formula: C19H24N4O4S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 critical for complex formation with Cdc20. It can also inhibited the Mad2-F-Mbp1 interaction in FP assays.
Molecular Weight: 404, 49
