Mal-C6-α-Amanitin | T18249

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Mal-C6-α-Amanitin | T18249 | TargetMol Chemicals

CAS: 1578249-76-9

Smiles: [H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CS(=O)c3[nH]c4cc(OCCCCCCNC(=O)CCCCCN5C(=O)C=CC5=O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1

Formula: C55H78N12O17S

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6.

Molecular Weight: 1211, 36

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