Product Overview
Mambalgin 1 | TP2003 | TargetMol Chemicals
CAS: 1609937-15-6
Smiles:
Formula: C272H429N85O84S10
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively). Binds to closed/inactive channel. Selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Increases latency of withdrawal response in mouse tail-flick and paw-flick tests. Analgesic.
Molecular Weight: 6554, 51
