Product Overview
MG-132 | T2154 | TargetMol Chemicals
CAS: 133407-82-6
Smiles: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O
Formula: C26H41N3O5
Pathway: Apoptosis|||Autophagy|||Proteases/Proteasome|||Ubiquitination
Target: Apoptosis|||Proteasome|||Autophagy
Receptor: N/A
Bioactivity: MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain (IC50: 1.2 μM).
Molecular Weight: 475, 63
