Product Overview
Midostaurin | T3211 | TargetMol Chemicals
CAS: 120685-11-2
Smiles: CO[C@@H]1[C@@H](C[C@@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
Formula: C35H30N4O4
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling|||Others
Target: Others|||PKC
Receptor: N/A
Bioactivity: PKC412(Midostaurin; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.
Molecular Weight: 570, 649
