Product Overview
Moracin O | TN1951 | TargetMol Chemicals
CAS: 123702-97-6
Smiles: CC(C)(O)[C@H]1Cc2cc3cc(oc3cc2O1)-c1cc(O)cc(O)c1
Formula: C19H18O5
Pathway: Angiogenesis|||Chromatin/Epigenetic
Target: HIF
Receptor: N/A
Bioactivity: Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.
Molecular Weight: 326, 348
