Product Overview
Moracin T | TN4582 | TargetMol Chemicals
CAS: 1146113-27-0
Smiles: COc1c(O)cc2oc(cc2c1CC=C(C)C)-c1cc(O)cc(O)c1
Formula: C20H20O5
Pathway: Cell Cycle/Checkpoint|||Immunology/Inflammation|||Neuroscience
Target: c-Myc|||COX
Receptor: N/A
Bioactivity: Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermore can significantly suppress the elevation in 4-HNE level and elevate expression of c-fos, c-myc and cycloxygenase-2 (COX-2) in normal epidermis induced by double application of TPA; the moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
Molecular Weight: 340, 4
