Product Overview
MRT-10 | T23027 | TargetMol Chemicals
CAS: 330829-30-6
Smiles: COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1cccc(NC(=O)c2ccccc2)c1
Formula: C24H23N3O5S
Pathway: GPCR/G Protein|||Stem Cells
Target: Hedgehog/Smoothened
Receptor: N/A
Bioactivity: MRT 10 is a smoothened (Smo) receptor antagonist (an IC50 = 0.5 μM in HEK293 cells transiently expressing mouse Smo). It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (an IC50 = 0.5 μM
Molecular Weight: 465, 52
