Product Overview
MS049 2HCl (1502816-23-0(free base)) | T4393 | TargetMol Chemicals
CAS: T4393
Smiles: Cl.Cl.CNCCN1CCC(CC1)OCc2ccccc2
Formula: C15H26Cl2N2O
Pathway: Chromatin/Epigenetic
Target: Histone Methyltransferase
Receptor: N/A
Bioactivity: MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 μM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.
Molecular Weight: 321, 28
