Product Overview
BMS 599626 2HCl (873837-23-1(HCl)) | T5398 | TargetMol Chemicals
CAS: T5398
Smiles: Cl.Cl.Cc1c(NC(=O)OC[C@@H]2COCCN2)cn2ncnc(Nc3ccc4n(Cc5cccc(F)c5)ncc4c3)c12
Formula: C27H29Cl2FN8O3
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: HER
Receptor: N/A
Bioactivity: BMS-599626 (AC480) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100-fold to Lck, VEGFR2, c-Kit, MET, etc.
Molecular Weight: 603, 47
