Product Overview
MSN-125 | T16155 | TargetMol Chemicals
CAS: 1592908-16-1
Smiles: COCCOCOc1ccc2[C@@H]([C@@H](CN)Oc2c1)N(Cc1ccc(Br)cc1)C(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
Formula: C36H38BrN3O6
Pathway: Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Target: Akt
Receptor: N/A
Bioactivity: MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) (IC50: 4 μM).
Molecular Weight: 688, 619
