Product Overview
SP-96 | T41256 | TargetMol Chemicals
CAS: 2682114-54-9
Smiles: Cn1ncc(-c2ccc3c(Nc4cccc(NC(Nc5cccc(F)c5)=O)c4)ncnc3c2)c1
Formula: C25H20FN7O
Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic
Target: Aurora Kinase
Receptor: N/A
Bioactivity: SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM). SP-96 can be used in triple negative breast cancer studies.
Molecular Weight: 453, 47
