Product Overview
N-piperidine Ibrutinib | T9408 | TargetMol Chemicals
CAS: 330785-90-5
Smiles:
Formula: N/A
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: BTK
Receptor: N/A
Bioactivity: N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
Molecular Weight: N/A
