NCT-502 | T16277

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TMC-T16277
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Product Overview

NCT-502 | T16277 | TargetMol Chemicals

CAS: 1542213-00-2

Smiles: Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1

Formula: C18H20F3N5S

Pathway: Metabolism

Target: Dehydrogenase

Receptor: N/A

Bioactivity: NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 Ī¼M against PHGDH.

Molecular Weight: 395, 45

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