Product Overview
NCT-502 | T16277 | TargetMol Chemicals
CAS: 1542213-00-2
Smiles: Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1
Formula: C18H20F3N5S
Pathway: Metabolism
Target: Dehydrogenase
Receptor: N/A
Bioactivity: NCT-502 is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 μM against PHGDH.
Molecular Weight: 395, 45
