Product Overview
Neratinib | T2325 | TargetMol Chemicals
CAS: 698387-09-6
Smiles: CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
Formula: C30H29ClN6O3
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||HER
Receptor: N/A
Bioactivity: Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.
Molecular Weight: 557, 05
