Product Overview
NI-57 | TQ0083 | TargetMol Chemicals
CAS: 1883548-89-7
Smiles: COc1cc(ccc1S(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C#N
Formula: C19H17N3O4S
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain
Receptor: N/A
Bioactivity: NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
Molecular Weight: 383, 42