Product Overview
Ningetinib Tosylate | TQ0041 | TargetMol Chemicals
CAS: 1394820-77-9
Smiles: Cc1ccc(cc1)S(O)(=O)=O.Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C
Formula: C38H37FN4O8S
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||c-Met/HGFR|||TAM Receptor
Receptor: N/A
Bioactivity: Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
Molecular Weight: 728, 79