Product Overview
Ningetinib | TQ0021 | TargetMol Chemicals
CAS: 1394820-69-9
Smiles: Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C
Formula: C31H29FN4O5
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||c-Met/HGFR|||TAM Receptor
Receptor: N/A
Bioactivity: Ningetinib (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
Molecular Weight: 556, 594
