Ningetinib | TQ0021

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TMC-TQ0021
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Product Overview

Ningetinib | TQ0021 | TargetMol Chemicals

CAS: 1394820-69-9

Smiles: Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(OCC(C)(C)O)ccc34)c(F)c2)c(=O)n(-c2ccccc2)n1C

Formula: C31H29FN4O5

Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors

Target: VEGFR|||c-Met/HGFR|||TAM Receptor

Receptor: N/A

Bioactivity: Ningetinib (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.

Molecular Weight: 556, 594

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