Product Overview
Nintedanib | T1777 | TargetMol Chemicals
CAS: 656247-17-5
Smiles: COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1
Formula: C31H33N5O4
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FGFR|||FLT|||PDGFR|||Src
Receptor: N/A
Bioactivity: Nintedanib is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFRα/β, respectively).
Molecular Weight: 539, 636
