Product Overview
NSC 66811 | T21578 | TargetMol Chemicals
CAS: 6964-62-1
Smiles: Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1
Formula: C23H20N2O
Pathway: Apoptosis
Target: Mdm2
Receptor: N/A
Bioactivity: NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.
Molecular Weight: 340, 426
