Product Overview
NSC-87877 disodium | T6911 | TargetMol Chemicals
CAS: 56932-43-5
Smiles: [Na+].[Na+].Oc1c(cc(c2cccnc12)S([O-])(=O)=O)\N=N\c1ccc2cc(ccc2c1)S([O-])(=O)=O
Formula: C19H11N3Na2O7S2
Pathway: Apoptosis|||Metabolism
Target: Apoptosis|||Phosphatase
Receptor: N/A
Bioactivity: NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Molecular Weight: 503, 41
