Product Overview
Pamapimod | T6927 | TargetMol Chemicals
CAS: 449811-01-2
Smiles: Cn1c2nc(NC(CCO)CCO)ncc2cc(Oc2ccc(F)cc2F)c1=O
Formula: C19H20F2N4O4
Pathway: Autophagy|||MAPK
Target: p38 MAPK|||Autophagy
Receptor: N/A
Bioactivity: Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.
Molecular Weight: 406, 39
