Product Overview
Paraxanthine | T4973 | TargetMol Chemicals
CAS: 611-59-6
Smiles: Cn1cnc2[nH]c(=O)n(C)c(=O)c12
Formula: C7H8N4O2
Pathway: Metabolism
Target: Endogenous Metabolite
Receptor: N/A
Bioactivity: Paraxanthine is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of caffeine. Also Paraxanthine acts as a competitive phosphodiesterase inhibitor, which increases intracellular cAMP, activates PKA, inhibits TNF-α and leukotriene synthesis. In addition, Paraxanthine acts as a Na+/K+ ATPase enzymatic effector.
Molecular Weight: 180, 167