Product Overview
PD-089828 | T8976 | TargetMol Chemicals
CAS: 179343-17-0
Smiles: CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl
Formula: C18H18Cl2N6O
Pathway: Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||FGFR|||PDGFR|||Src
Receptor: N/A
Bioactivity: PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
Molecular Weight: 405, 28
