Product Overview
PDK1-IN-RS2 | T16450 | TargetMol Chemicals
CAS: 1643958-89-7
Smiles: Clc1ccc2nc(NS(=O)(=O)c3cc4ccccc4s3)sc2c1
Formula: C15H9ClN2O2S3
Pathway: PI3K/Akt/mTOR signaling
Target: PDK
Receptor: N/A
Bioactivity: PDK1-IN-RS2 inhibits the activation of the downstream kinases S6K1 by PDK1. PDK1-IN-RS2 is a mimic of the peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor (Kd: 9 μM).
Molecular Weight: 380, 88
