Product Overview
pep2-SVKI | TP1944 | TargetMol Chemicals
CAS: 328944-75-8
Smiles:
Formula: C60H93N13O18
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).
Molecular Weight: 1284, 47
