Product Overview
Pexmetinib | T6934 | TargetMol Chemicals
CAS: 945614-12-0
Smiles: Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2n(CCO)ncc2c1)C(C)(C)C
Formula: C31H33FN6O3
Pathway: Autophagy|||MAPK|||Tyrosine Kinase/Adaptors
Target: Tie-2|||p38 MAPK|||Autophagy
Receptor: N/A
Bioactivity: Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
Molecular Weight: 556, 642
