Product Overview
PF 05089771 | T7502L | TargetMol Chemicals
CAS: 1235403-62-9
Smiles: Nc1n[nH]cc1-c1cc(Cl)ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1
Formula: C18H12Cl2FN5O3S2
Pathway: Membrane transporter/Ion channel
Target: Sodium Channel
Receptor: N/A
Bioactivity: PF-05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.
Molecular Weight: 500, 34
