Product Overview
PPADS tetrasodium | T16564 | TargetMol Chemicals
CAS: 192575-19-2
Smiles: [Na+].[Na+].[Na+].[Na+].Cc1nc(\N=N\c2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O
Formula: C14H10N3Na4O12PS2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca2 exchanger in guinea pig airway smooth muscle. PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 (IC50s ranging from 1 to 2.6 μM). PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) and recombinant P2Y4 (IC50~15 mM) receptors.
Molecular Weight: 599, 3
