Product Overview
Praeruptorin A | T3777 | TargetMol Chemicals
CAS: 73069-27-9
Smiles: C\C=C(\C)C(=O)O[C@H]1[C@@H](OC(C)=O)c2c(OC1(C)C)ccc1ccc(=O)oc21
Formula: C21H22O7
Pathway: Neuroscience|||NF-Κb
Target: CaMK|||NF-κB
Receptor: N/A
Bioactivity: Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
Molecular Weight: 386, 4
