Product Overview
Praeruptorin E | T4S1422 | TargetMol Chemicals
CAS: 78478-28-1
Smiles: C\C=C(\C)C(=O)O[C@H]1[C@@H](OC(=O)CC(C)C)c2c(OC1(C)C)ccc1ccc(=O)oc21
Formula: C24H28O7
Pathway: Membrane transporter/Ion channel|||Metabolism|||Others
Target: Others|||Calcium Channel
Receptor: N/A
Bioactivity: 1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activity. 2. Praeruptorin D and E can protect mice from hydrochloric acid (HCl)-induced lung injury by inhibiting polymorphonuclear leukocytes (PMNs) influx, IL-6 release and protein exudation, suggest that they may be useful in the therapy of lung injury.
Molecular Weight: 428, 481
