Product Overview
Proteasome inhibitor IX | T21854 | TargetMol Chemicals
CAS: 856849-35-9
Smiles: O=C(/C(CN(C)C/1)=C\C2=CC=C(B(O)O)C=C2)C1=C/C3=CC=C(B(O)O)C=C3
Formula: C20H21B2NO5
Pathway: Proteases/Proteasome|||Ubiquitination
Target: Proteasome
Receptor: N/A
Bioactivity: AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). AM 114 shows potent anticancer activity. AM 114 exhibits HCT116 p53+/+ cells growth inhibitory activity(IC50 = 1.49 μM).
Molecular Weight: 377, 01
