Product Overview
Protopine hydrochloride | TMA1944 | TargetMol Chemicals
CAS: 6164-47-2
Smiles: Cl.CN1CCc2cc3OCOc3cc2C(=O)Cc2ccc3OCOc3c2C1
Formula: C20H20ClNO5
Pathway: Angiogenesis|||GPCR/G Protein|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: EGFR|||cAMP
Receptor: N/A
Bioactivity: Protopine has antiplatelet effects, which is due to inhibition on thromboxane formation and phosphoinositides breakdown and then lead to the decrease of intracellular calcium concentration.Protopine seems to inhibit the heterotypic cell adhesion between MDA-MB-231 cells, and human umbilical vein endothelial cells by changing the expression of adhesive factors.
Molecular Weight: 389, 83
