Product Overview
PTC-209 hydrobromide | T6178 | TargetMol Chemicals
CAS: 1217022-63-3
Smiles: Br.COc1cc(Br)c(Nc2nc(cs2)-c2c(C)nc3ncccn23)c(Br)c1
Formula: C17H14Br3N5OS
Pathway: Autophagy|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Target: BMI-1|||Autophagy
Receptor: N/A
Bioactivity: PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
Molecular Weight: 576, 11
